Abstract
The mixture of the sec. amine (IVa) and the tert. amine (IVb) is easily separated by treatment with ethyl chloroformate (III) leading to (IVb)·HCl and the soluble ester (IVc) (no yield given) which is reduced to (IVd).
- Title
- The Nitrogen Inversion Barrier of 7‐Methyl‐7‐azabicyclo(2.2.1)heptane (IVd) and the “Bicyclic Effect”
- Author/Creator
- S. F. Nelsen - University of Wisconsin–MadisonJ. T. Ippoliti - University of Wisconsin–MadisonT. B. Frigo - University of Wisconsin–MadisonP. A. Petillo - University of Wisconsin–Madison
- Publication Details
- ChemInform, Vol.20(23), pp.no-no
- Publisher
- WILEY‐VCH Verlag GmbH
- Number of pages
- 1
- Academic Unit
- Biochemistry; Chemistry
- Language
- English
- Resource Type
- Journal article
- Record Identifier
- 991015166143603691